It is scientific common sense that food can supplement NMN and convert it into NAD+ Supplement. But why do we still need to consume NMN nutritional supplements? This article introduces the NMN content in food and how much NAD+ substances are converted. As we age and our stomachs weaken, the efficiency of this conversion gradually decreases, causing our body functions to decline, our immunity to weaken, our physical fitness to fail to keep up, and our organs to be damaged. Balancing NAD+ levels is an important indicator of anti-aging.

Nicotinamide adenine dinucleotide (NAD+) is an extremely important chemical in our energy metabolism, such as when we oxidize fatty acids to produce energy. On the other hand, scientists discovered nicotinamide mononucleotide (NMN) as a precursor to NAD+ in 1963 and have shown that it can increase NAD+ levels. NMN is naturally present in many plant and animal food sources, such as broccoli or shrimp.

Key Information

NMN is an important chemical in the human body that helps maintain NAD+ levels. It is a key molecule used for DNA repair and energy metabolism, among other things, and is present in all living cells.

Although NMN has been shown to have many benefits, most of the benefits have been shown in rodent studies, and its optimal dose and suitability for humans are still being studied.

Current studies show that NMN is non-toxic and has few side effects (of course, make sure the NMN supplement you take is real).

NMN can be ingested by eating fruits and vegetables, such as cabbage and edamame (immature soybeans) or foods from animal sources, such as beef and shrimp.

What is NMN?

NMN is a precursor to NAD+ and has been shown to be involved in more than half of physiological processes, helping to activate enzymes involved in different disease processes, DNA repair or age-related processes. The body synthesizes NMN from vitamin B3; however, this process is relatively slow, so it creates a bottleneck for NAD+ metabolism. Therefore, it is also logical that the benefit of NMN supplements lies in increasing NAD+ levels.

NMN vs. NAD+ vs NMNH: What's the difference?

In simple terms, there is no life without NAD+. NAD+ is present in all living cells and is primarily responsible for transporting electrons during energy production. Because NAD+ is so important, it is not only synthesized directly from tryptophan or aspartate, but it is also recycled. NMN plays a role in this recycling process and plays a role in the most critical step of this recycling pathway. Therefore, NMN helps prevent the decline of NAD+ levels and ensures the proper functioning of this critical recycling pathway.

Benefits of NMN

Since NAD+ is essential for all life, NMN has attracted a lot of interest. NAD+ levels decline with age, and boosting NAD+ in worms and fruit flies has been shown to increase lifespan. Additionally, NMN supplementation has been shown to have extraordinary therapeutic effects on various metabolic processes. From an insulin and diabetes perspective, NMN has been shown to ameliorate impairments in insulin secretion and improve insulin action. Additionally, NMN has been shown to protect the heart from ischemia/reperfusion injury, such as that which may occur during a heart attack. NMN has also been shown to improve mitochondrial and cognitive function in a mouse model of Alzheimer's disease, improve hearing loss, maintain muscle stem cell function, and prevent DNA damage and the formation of hepatocellular carcinoma.

Where can you get NMN?

NMN occurs naturally and is found in many foods, such as healthy vegetables, nutritious fruits, and some animal foods. Additionally, due to the increased interest in NMN and the scientific research surrounding it, there are now countless supplements containing NMN.
However, not all supplements are properly tested, so it is the consumer's responsibility to ensure that the supplement has not been adulterated. The FDA has published a list of adulterated supplements, which includes some NMN supplements.
For example, Hello100 offers NMN supplements in a bioavailable form that has been tested and approved by an independent laboratory.

Foods rich in NMN

NMN is mainly found in vegetables such as cabbage, broccoli and cucumber, and fruits such as avocado and tomato:

Does NMN have side effects?

In numerous rodent studies, NMN has no apparent toxicity or serious side effects. Unlike other metabolites in NAD+ metabolism, such as NA and nicotinamide (NAM), which may cause liver damage and flushing, a single dose of 100-500 mg of NMN in healthy adults has not found any side effects.

How to take NMN to be effective? Analysis of previous studies.
Does NMN cause cancer?

There is concern about whether NMN causes or promotes cancer by enhancing NAD+ in cancer cells and potentially conferring certain types of immunity. However, several studies have shown that NMN does not prevent lung cancer formation, nor does it inhibit tumor growth or promote tumor growth in mouse models. So, at the very least, NMN has no negative cancer effects and, in some cases, may have some protective effects.

How to Increase NAD+ Levels Naturally?

One of the best ways to naturally increase NAD+ levels is to perform regular aerobic exercise. Exercise training increases nicotinamide phosphoribosyltransferase (NAMPT), the bottleneck enzyme in the NAD+ salvage pathway, where NMN works. Interestingly, in the same context, a study in a mouse model of obesity showed that nine weeks of exercise and 18 days of NMN injections had similar benefits on metabolic dysfunction and liver fat metabolism. In addition, calorie restriction has also been shown to extend lifespan and increase NAD+ levels, especially when supplemented with a healthy diet rich in vitamin B3 or tryptophan. Finally, making sure to get enough sleep with a proper circadian rhythm has also been shown to ensure high levels of NAD+.

The Best Way to Take NMN: Supplement or Diet

In various human studies, doses of up to 600 mg of NMN have been used. However, there appear to be different optimal doses depending on the desired outcomes elucidated by different studies. As with most other metabolic processes, a balanced, healthy diet that includes hydrated fruits, tasty and nutritious vegetables, and protein from animal sources is the best way to ensure you get enough NMN. It is also appropriate to increase your daily intake of NMN supplements if you trust the source of the supplement and certify its applicable purity and potency.

The content of NMN in food is too low. After a series of gastrointestinal digestion and loss, the actual conversion of NMN into NDA+ is reduced by 30-40%, the human blood is diluted by 20%, and the NAD+ entering the cell is about 40%. However, as the human body ages, the ability of our various organs to function becomes lazy, and this NAD+ substance will be further reduced, forming a vicious circle.

This is the reason: the reason to buy NMN 18000!
We must maintain a balanced NAD+ level and fully absorb substances from NMN / NMNH. Increase immunity, resistance, maintain vitality, restore body organ function, and delay aging.